AGLIT was initiated by the college of medicine in Malawi and Liverpool School of Tropical Medicine (UK) in response to a study which found a strong link. The original curriculum comprises of literacy, numeracy between illiteracy and poor adolescent health outcomes. The original curriculum comprised of literacy, numeracy and health education only but the curriculum has been revised and includes, Life Skills, Nutrition and HIV/AIDS. Youth Clubs were developed as a vital sequel to classes to reinforce girls learning, income generation. Income because a chief youth club activity since poverty prevents girls from accessing health services and applying their health knowledge.

The impact of AGLIT teaching has extended beyond the targeted adolescent girls to the wider community. Girls pass on health messages to villages and illiterate boys were invited to join AGLIT classes from 2002. Regular meetings with District Executive committees, Community leaders, Religious leaders, Village Education Committees (VECs) and other stakeholder to provide opportunities to discuss sexual health curriculum with cultural gatekeepers since traditional practices hinder young people's safe behaviour.